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cbd-Broad-Spectrum-vs-Full-Spectrum

Broad Spectrum vs. Full Spectrum: Everything You Need to Know

cbd-Broad-Spectrum-vs-Full-Spectrum

As CBD has become increasingly popular, scientists and consumers alike are becoming more sophisticated about the substance and its effects. The terms “broad spectrum” and “full spectrum” have become part of the vernacular for discussing CBD. Unfortunately, the information about these terms can be confusing and lead to misconceptions about the value and realities of broad spectrum and full spectrum products.

What do these terms mean?

To put these terms into context, it is important to know that they refer to what exactly you are getting in a CBD product. The purest form of CBD is referred to as CBD isolate. The way that CBD isolate is obtained is by taking CBD from the cannabis plant and separating it from all the other substances that naturally occur in the plant.

Full spectrum CBD, on the other hand, refers to an extract that includes all the substances that are naturally present in the plant without the bioactive profile of these compounds being compromised. The other substances that can be found with CBD are other cannabinoids as well as essential oils and terpenes.

Until less than 15 years ago, it was believed that CBD isolate was more effective than full spectrum CBD in achieving some of its outcomes. However, critical research in the early 2000s showed that full spectrum CBD led to higher levels of pain relief than did CBD isolate.

These observations led to the notion that the active compounds in cannabis work together to produce what has been referred to as an entourage effect, where the presence of certain substances increase the activity of others. This concept of cannabis synergy might also help to account for why botanical drugs are frequently observed to be more effective than their isolated substances.

So why not just use full spectrum CBD products?

Though full spectrum CBD may offer specific benefits over CBD isolate, full spectrum CBD products contain tetrahydrocannabinol (THC), which is the psychoactive ingredient in cannabis that is associated with the “high” of marijuana use. The U.S. Food and Drug Administration (FDA) allows CBD products to be used and distributed, but these products have to limit their concentration of THC.

Broad spectrum CBD may offer an opportunity to get some of the benefits of full spectrum CBD while avoiding the practical and legal challenges that THC presents. Like full spectrum CBD, broad spectrum CBD includes other substances naturally present with CBD. However, unlike full spectrum CBD, broad spectrum products do not contain THC.

Takeaways

  • Pure CBD appears to be less effective in achieving desirable outcomes than CBD that occurs along with the other elements that naturally occur with it.
  • Full spectrum CBD contains CBD and all other elements that naturally occur with CBD.
  • Broad spectrum CBD contains CBD and all other elements that naturally occur with CBD except THC, making it potentially both compliant with CBD regulations and more effective than pure CBD isolate.

    References

    1. Pavlovic R, Nenna G, Calvi L, et al. Quality Traits of “Cannabidiol Oils”: Cannabinoids Content, Terpene Fingerprint and Oxidation Stability of European Commercially Available Preparations. Molecules. 2018;23(5). doi:10.3390/molecules23051230
    2. Russo EB. The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain. Front Plant Sci. 2018;9:1969. doi:10.3389/fpls.2018.01969
    3. Ben-Shabat S, Fride E, Sheskin T, et al. An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. Eur J Pharmacol. 1998;353(1):23-31. doi:10.1016/s0014-2999(98)00392-6
    4. Mechoulam R, Ben-Shabat S. From gan-zi-gun-nu to anandamide and 2-arachidonoylglycerol: the ongoing story of cannabis. Nat Prod Rep. 1999;16(2):131-143. doi:10.1039/a703973e
    5. Bonn-Miller MO, ElSohly MA, Loflin MJE, Chandra S, Vandrey R. Cannabis and cannabinoid drug development: evaluating botanical versus single molecule approaches. Int Rev Psychiatry. 2018;30(3):277-284. doi:10.1080/09540261.2018.1474730
    6. Health effects of cannabis and cannabinoids: The current state of evidence and recommendations for research. National Academies of Sciences, Engineering, and Medicine. https://www.ncbi.nlm.nih.gov/books/NBK425762/. Published 2017. Accessed November 30, 2019.
    7. FDA regulation of cannabis and cannabis-derived products, including cannabidiol (CBD). FDA.gov. https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd. Accessed November 30, 2019.
    8. Gallily, R, Yekhtin, Z, & Hanus L. Overcoming the bell-shaped dose-response of cannabidiol by using cannabis extract enriched by cannabidiol. Pharmacol Pharm. 2015;6:75-85.
    9. Burstein S. Cannabidiol (CBD) and its analogs: a review of their effects on inflammation. Bioorg Med Chem. 2015;23(7):1377-1385. doi:10.1016/j.bmc.2015.01.059
    10. ElSohly MA, Radwan MM, Gul W, Chandra S, Galal A. Phytochemistry of Cannabis sativa L. Prog Chem Org Nat Prod. 2017;103:1-36. doi:10.1007/978-3-319-45541-9_1
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