• Free Shipping on all orders! | Customer Service: 855-921-7254
  • My Account
pure-usa-logopure-usa-logopure-usa-logopure-usa-logo
  • Shop
    • CBD Oil
    • Capsules
    • Gummies
    • Topicals
    • Pet
    • Vapes
    • Subscribe
  • Learn
    • What is CBD
    • Blog
    • CBD Quiz
    • About us
  • Partner
    • Become a Retailer
    • Become an Affiliate
  • Support
    • Contact
    • FAQ
    • Batch Reports
0
cbd-Broad-Spectrum-vs-Full-Spectrum
Broad Spectrum vs. Full Spectrum: Everything You Need to Know
December 5, 2019
cbd-for-pets
CBD Efficacy in Pets
January 20, 2020
Published by PureUSA on January 20, 2020
Categories
  • Blog
Tags
cbd-for-joint-pain-relief

CBD for Joint Pain in Adults

cbd-for-joint-pain-relief

Joint pain is a prevalent malady amongst adult, especially as they get older. Though there are several medical interventions that are offered to cope with this type of pain – including drugs and surgery – these options are limited in their effectiveness, are associated with risks and side effects, and can be costly. 

Scrivener Crack

Recent research has pointed to the potential for CBD to help overcome some of these weaknesses observed in conventional joint pain management strategies. While this area of research is still new, there is some evidence that products containing CBD may help to reduce pain and to manage chronic pain. Topical CBD products, for instance, have been shown to inhibit pain in people with osteoarthritis.

How might CBD achieve pain reduction in people suffering from arthritis and joint pain?

The endocannabinoid system is well-known for regulating inflammation and pain, and CBD acts on the receptors of this system – called cannabinoid receptors – which are located throughout the body.

  • CBD may combat problematic inflammation

CBD is an antioxidant with beneficial anti-inflammatory properties,  and one way CBD is likely to alleviate joint pain is by  reducing inflammation. Indeed, inflammation is often a cause of joint pain and occurs when the immune system is overly active. Its ability to reduce inflammation, by halting certain immune responses, may enable CBD to protect nerves and thereby prevent pain.

  • CBD may inhibit pain pathway signaling

Another way CBD appears capable of minimizing pain is by affecting the interaction between certain stimuli and pain receptors in the nervous system. Data suggest that this action of CBD changes people’s perception of pain such that the pain receptors are less sensitive , resulting in reduced joint pain. Joint pain has specifically been shown to be influenced by the interaction of  CB2 receptors and nearby TRPV1 channels. These types of observations not only support the potential value of CBD for joint pain but also help demonstrate how CBD may confer such benefits.

Interestingly, joint pain is the most common condition for which medical cannabis is requested. However, many people do not want to deal with the psychoactive features of cannabis that come from the substance’s THC. CBD, which is not psychoactive, may provide a unique opportunity for these people to achieve the pain benefits associated with cannabis without experiencing mind effects.

Takeaway

Research, including preclinical and clinical work, has started to show that CBD can prevent joint pain. However, more research is needed before we can understand exactly if and how CBD can relieve joint pain in adult patients.

References
  1. Lowin T, Schneider M, Pongratz G. Joints for joints: cannabinoids in the treatment of rheumatoid arthritis. Curr Opin Rheumatol. 2019;31(3):271-278. doi:10.1097/BOR.0000000000000590
  2. Miller RJ, Miller RE. Is cannabis an effective treatment for joint pain? Clin Exp Rheumatol. 2017;35 Suppl 107(5):59-67.
  3. Philpott HT, O’Brien M, McDougall JJ. Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis. Pain. 2017;158(12):2442-2451. doi:10.1097/j.pain.0000000000001052
  4. Russo EB. Cannabinoids in the management of difficult to treat pain. Ther Clin Risk Manag. 2008;4(1):245-259. doi:10.2147/tcrm.s1928
  5. Nagarkatti P, Pandey R, Rieder SA, Hegde VL, Nagarkatti M. Cannabinoids as novel anti-inflammatory drugs. Future Med Chem. 2009;1(7):1333-1349. doi:10.4155/fmc.09.93
  6. Bruni N, Della Pepa C, Oliaro-Bosso S, Pessione E, Gastaldi D, Dosio F. Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules. 2018;23(10). doi:10.3390/molecules23102478
  7. Malfait AM, Gallily R, Sumariwalla PF, et al. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proc Natl Acad Sci U S A. 2000;97(17):9561-9566. doi:10.1073/pnas.160105897
  8. Schuelert N, McDougall JJ. The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55. Neurosci Lett. 2011;500(1):72-76. doi:10.1016/j.neulet.2011.06.004
  9. Schuelert N, McDougall JJ. Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees. Arthritis Rheum. 2008;58(1):145-153. doi:10.1002/art.23156
  10. Muller C, Morales P, Reggio PH. Cannabinoid Ligands Targeting TRP Channels. Front Mol Neurosci. 2018;11:487. doi:10.3389/fnmol.2018.00487
Share
1

Related posts

cbd-for-pets
January 20, 2020

CBD Efficacy in Pets


Read more
cbd-Broad-Spectrum-vs-Full-Spectrum
December 5, 2019

Broad Spectrum vs. Full Spectrum: Everything You Need to Know


Read more
does-cbd-show-up-on-drug-tests
December 5, 2019

High Quality CBD Products Don’t Lead to Failed Drug Tests


Read more
SIGN UP AND KEEP UP TO DATE

News, Tips, Updates and all things CBD

Enter your email address to receive our PureUSA newsletter.

Pure USA CBD

Shop
Tinctures
Capsules
Gummies
Topicals
Partner
Learn
Support
Contact

Privacy Policy
Shipping & Returns
Terms of Services
CBD Affiliate Program
Become a Retailer
About Us

PAYMENTS ACCEPTED

Credit Cards Accepted

Contact Us
PureUSA Company
6105 S Main St, Suite 200
Aurora, CO 80016

Customer Service
855-921-7254
info@PureUSA.com

The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.

© 2019 PureUSA

    0
    • My Account